6–11 Dec 2026
Stellenbosch University
Africa/Johannesburg timezone

Clinical Data Classification with Quantum Kernel Alignment

Not scheduled
20m
Jan Mouton Learning Centre (Stellenbosch University)

Jan Mouton Learning Centre

Stellenbosch University

Poster

Speaker

Florian Heininger

Description

Quantum kernel methods are among the most promising near-term applications of quantum machine learning, with the quantum feature map controlling a model's ability to capture meaningful correlations from little labelled data. We present a systematic approach that aligns a quantum-inspired feature map to highly imbalanced and scarce clinical datasets through kernel--target alignment (KTA) optimization, and feeds the resulting Gram matrix into a classical support vector machine (SVM). On six clinical datasets of therapeutic and prognostic relevance that are effectively intractable for a classical radial basis function (RBF) kernel SVM, the aligned quantum kernel improves the AUC by $\approx 0.22$ on average, while matching the classical baseline on a balanced benchmark. This suggests a practical NISQ-era pathway to analyze complex clinical data that is otherwise resistant to conventional machine learning.

Topic Quantum kernel methods and their applications

Author

Co-authors

Dr Jeanette Miriam Lorenz (Fraunhofer IKS) Prof. Matthias Weidemüller (Heidelberg University) Prof. Niels Halama (DKFZ)

Presentation materials